Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
-
MGMT MUTATION
MGMT MUTATION - Associated Disease
- Glioblastoma multiforme
- Source Database
- DisGeNET
- Description
- We performed a systematic review to identify articles from the temozolomide era (2005-present) that reported survival data related to treatment of elderly patients with GBM using either temozolomide alone or radiotherapy alone, with consideration of O6-methylguanine-DNA-methyltransferase gene (MGMT) promoter methylation status.
- Pubmed
- 25822375
- Section of the abstract supporting the evidence
- EVIDENCE REVIEW
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0105862330111318
Drugs