Annotation Detail

Information
Associated Genes
TCF7L2
Associated Variants
TCF7L2 MUTATION
TCF7L2 MUTATION
Associated Disease
Neurodevelopmental Disorders
Source Database
DisGeNET
Description
To demonstrate adult brain function, we performed expression analyses and ChIPseq in human neural stem cell(NSC) lines at different developmental stages and adult human brain, targeting two genes associated with NDDs, SATB2 and EHMT1, and the WNT signaling gene TCF7L2, which has not been associated with NDDs.
Pubmed
26194112
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs