Annotation Detail

Information
Associated Genes
GRN
Associated Variants
GRN c.*78C>T ( ENST00000589265.5, ENST00000053867.8 )
GRN c.*78C>T ( ENST00000053867.8, ENST00000589265.5 )
Associated Disease
Frontotemporal Lobar Degeneration
Source Database
DisGeNET
Description
The purpose of this meta-analysis was to investigate the association between progranulin polymorphism rs5848 and risk of the neurodegenerative diseases frontotemporal lobar degeneration (FTLD), Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS).
Pubmed
25578179
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.173094324449216
Year of publication
2014
Drugs