Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA MUTATION
VEGFA MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
To characterize the population pharmacokinetics of bevacizumab, its binding properties to VEGF165 and the effect of demographic data and VEGF-A polymorphisms on the interplay between bevacizumab serum pharmacokinetics and VEGF165 serum concentrations in patients with colorectal cancer stage IV.
Pubmed
25687989
Section of the abstract supporting the evidence
PURPOSE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0535289257148537
Drugs