Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
In this study, we demonstrate that fos-related antigen-1 (Fra-1) plays a critical role in IL-6 induced CRC aggressiveness and epithelial-mesenchymal transition (EMT).
Pubmed
25750173
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0358092591595133
Drugs