Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
-
ABCB1 MUTATION
ABCB1 MUTATION - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- Chemoresistance in multidrug-resistant (MDR) cells over expressing P-glycoprotein (P-gp) encoded by the MDR1 gene, is a major obstacle to successful chemotherapy for colorectal cancer.
- Pubmed
- 24901713
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0447345033297608
Drugs