Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT MUTATION
MGMT MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
We applied artificial neural networks (ANNs) to understand the connections among polymorphisms of genes involved in folate metabolism, clinico-pathological features and promoter methylation levels of MLH1, APC, CDKN2A(INK4A), MGMT and RASSF1A in 83 sporadic colorectal cancer (CRC) tissues, and to link dietary and lifestyle factors with gene promoter methylation.
Pubmed
25942531
Section of the abstract supporting the evidence
AIMS
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0333226750490723
Drugs