Annotation Detail

Information
Associated Genes
LMNA
Associated Variants
LMNA p.Thr10Ile (p.T10I) ( ENST00000368300.9, ENST00000368301.6, ENST00000368299.7, ENST00000361308.9, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
LMNA p.Thr10Ile (p.T10I) ( ENST00000368301.6, ENST00000368299.7, ENST00000368300.9, ENST00000361308.9, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
Associated Disease
lipodystrophy
Source Database
DisGeNET
Description
Atypical generalized lipoatrophy and severe insulin resistance due to a heterozygous LMNA p.T10I mutation.
Pubmed
19169477
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0261080773280298
Year of publication
2008
Drugs