Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
Xenograft Model
Source Database
DisGeNET
Description
In transformed cells, enforced expression of SOCS3 or interfering with IL6 pathway via IL6R blockade inhibited tumor growth and metastasis in mouse xenograft models.
Pubmed
24531711
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs