Annotation Detail

Information
Associated Genes
CDH1
Associated Variants
CDH1 MUTATION
CDH1 MUTATION
Associated Disease
Type II Endometrial Adenocarcinoma
Source Database
DisGeNET
Description
These results indicate that absence of CDH1 and TP53 in endometrial cells initiates chronic inflammation, promotes tumor microenvironment development following the recruitment of macrophages and promotes aggressive ECs.
Pubmed
24998851
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs