Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
ICAM1 p.Lys469Glu (p.K469E) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Lys469Glu (p.K469E) ( ENST00000264832.8, ENST00000423829.2 )
Associated Disease
Inflammatory Bowel Diseases
Source Database
DisGeNET
Description
The frequency of well-known mutations (R702W, G908W and 1007fs in the NOD2 gene; K469E in the ICAM-1 gene, and Delta32 in the CCR5 gene) involved in IBD was tested in 45 patients with CD and 22 patients with UC.
Pubmed
18647548
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00690559893384649
Year of publication
2008
Drugs