Annotation Detail
Information
- Associated Genes
- ICAM1
- Associated Variants
-
ICAM1 p.Lys469Glu (p.K469E)
(
ENST00000264832.8,
ENST00000423829.2 )
ICAM1 p.Lys469Glu (p.K469E) ( ENST00000264832.8, ENST00000423829.2 ) - Associated Disease
- diabetic retinopathy
- Source Database
- DisGeNET
- Description
- A significantly higher frequency of the EE genotype of the K469E polymorphism of the ICAM-1 was found in the patients with PDR compared with those without diabetic retinopathy (OR = 2.0, 95% confidence interval [CI] = 1.1-3.5; P = 0.013), whereas the G241A polymorphism of the ICAM-1 gene failed to yield an association with PDR.
- Pubmed
- 18942221
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.139812713618452
- Year of publication
- 2008
Drugs