Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
-
TP53 MUTATION
TP53 MUTATION - Associated Disease
- Mammary Neoplasms
- Source Database
- DisGeNET
- Description
- We have predicted three deleterious coding non-synonymous single nucleotide polymorphisms rs11540654 (rs11540654>R110P), rs17849781 (rs17849781>P278A) and rs28934874 (rs28934874>P151T) in TP53 with a phenotype in breast tumors using computational tools SIFT, Polyphen-2 and MutDB.
- Pubmed
- 25105660
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,CTD_human,CTD_mouse,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.352996795634515
Drugs