Annotation Detail
Information
- Associated Genes
- JAZF1
- Associated Variants
-
KCNJ11 p.Lys23Glu (p.K23E)
(
ENST00000528731.1,
ENST00000339994.5,
ENST00000682350.1,
ENST00000682764.1 )
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
THADA p.Thr1187Ala (p.T1187A) ( ENST00000405006.8, ENST00000405975.7 )
JAZF1 c.115+39526A>G ( ENST00000283928.10 )
KCNJ11 p.Lys23Glu (p.K23E) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
THADA p.Thr1187Ala (p.T1187A) ( ENST00000405006.8, ENST00000405975.7 )
JAZF1 c.115+39526A>G ( ENST00000283928.10 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- Four type 2 diabetes SNPs were associated with colorectal cancer risk: rs7578597 (THADA), rs864745 (JAZF1), rs5219 (KCNJ11) and rs7961581 (TSPAN8, LGR5).
- Pubmed
- 21602532
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs