Annotation Detail

Information
Associated Genes
IL1A
Associated Variants
IL1A MUTATION
IL1A MUTATION
Associated Disease
Systemic onset juvenile chronic arthritis
Source Database
DisGeNET
Description
Additionally, DNA microarray technology led to our discovery that the interleukin (IL)-1 gene signature is associated with systemic juvenile idiopathic arthritis (sJIA) and to the use of IL-1 blockade with anakinra in this disease.
Pubmed
24839407
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs