Annotation Detail

Information
Associated Genes
KMT2A
Associated Variants
KMT2A MUTATION
KMT2A MUTATION
Associated Disease
childhood leukemia
Source Database
DisGeNET
Description
We validated GIPFEL for the five most common gene fusions associated with childhood leukemia (MLL-AF4, MLL-AF9, MLL-ENL, ETV6-RUNX1, and TCF3-PBX1).
Pubmed
25137060
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00271441872080303
Drugs