Annotation Detail
Information
- Associated Genes
- TLR4
- Associated Variants
-
TNFRSF13C p.Pro21Arg (p.P21R)
(
ENST00000291232.5 )
ENSG00000285082 c.140+4295A>G, TLR4 p.Asp299Gly (p.D299G) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
ENSG00000285082 c.140+4595C>T, TLR4 p.Thr399Ile (p.T399I) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
TNFRSF13C p.Pro21Arg (p.P21R) ( ENST00000291232.5 )
ENSG00000285082 c.140+4295A>G, TLR4 p.Asp299Gly (p.D299G) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
ENSG00000285082 c.140+4595C>T, TLR4 p.Thr399Ile (p.T399I) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 ) - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- Interestingly, TLR4-D299G, TLR4-T399I and BAFFR-P21R carriage was associated with a lower risk of ICU-acquired sepsis.
- Pubmed
- 25454804
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.243539115231265
- Year of publication
- 2014
Drugs