Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
Liver regeneration disorder
Source Database
DisGeNET
Description
Elevated PPM1A levels led to attenuation of hPXR inhibition by tumor necrosis factor-α and cyclin-dependent kinase-2, which are known to be upregulated and essential during liver regeneration.
Pubmed
25561723
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs