Annotation Detail
Information
- Associated Genes
- STAT3
- Associated Variants
-
STAT3 MUTATION
STAT3 MUTATION - Associated Disease
- Chronic myeloproliferative disorder
- Source Database
- DisGeNET
- Description
- Our results demonstrate that JAK-STAT3-mediated cytokine production from malignant and nonmalignant cells contributes to MPN pathogenesis and that JAK inhibition in both populations is required for therapeutic efficacy.
- Pubmed
- 25572172
- Section of the abstract supporting the evidence
- SIGNIFICANCE
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs