Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
SERPINE1 MUTATION
SERPINE1 MUTATION
Associated Disease
Chronic myeloproliferative disorder
Source Database
DisGeNET
Description
Elevated levels of PAI-1 in MPN patients may result from its increased production by elevated number of activated platelets and vascular endothelial damage.
Pubmed
24509338
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs