Annotation Detail

Information
Associated Genes
APOE
Associated Variants
APOE MUTATION
APOE MUTATION
Associated Disease
Mild cognitive disorder
Source Database
DisGeNET
Description
Predictors of MCI were APOE ε4 allele (hazard ratio [HR] 1.89; p = 0.008), current depressive symptoms (HR 1.78; p = 0.02), midlife onset of hypertension (HR 2.43; p = 0.005), increasing number of vascular diseases (HR 1.13; p = 0.02), and chronic conditions from the Charlson Comorbidity Index (HR 1.08; p = 0.006).
Pubmed
25854867
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0400215073276435
Drugs