Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
EGFR MUTATION
EGFR MUTATION
Associated Disease
Squamous cell carcinoma of the head and neck
Source Database
DisGeNET
Description
Cetuximab is the only approved molecular targeting agent for HNSCC and despite ubiquitous expression of EGFR in HNSCC tumors, clinical responses are limited.
Pubmed
25826749
Section of the abstract supporting the evidence
EXPERT OPINION
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,CLINVAR
DisGENET score for the Gene Disease association
0.162616373916608
Drugs