Annotation Detail

Information
Associated Genes
ESR1
Associated Variants
ESR1 MUTATION
ESR1 MUTATION
Associated Disease
Malignant neoplasm of ovary
Source Database
DisGeNET
Description
E2-ERα activates all three arms of the UPR in breast and ovarian cancer cells in culture and in a mouse xenograft.
Pubmed
25263449
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0217589570281425
Drugs