Annotation Detail
Information
- Associated Genes
- STAT5B
- Associated Variants
-
STAT5B MUTATION
STAT5B MUTATION - Associated Disease
- Malignant neoplasm of ovary
- Source Database
- DisGeNET
- Description
- Pyrosequencing analyses confirmed that SGI-110 caused both global (LINE1) and gene-specific hypomethylation in vivo, including TSGs (RASSF1A), proposed drivers of ovarian cancer cisplatin resistance (MLH1 and ZIC1), differentiation-associated genes (HOXA10 and HOXA11), and transcription factors (STAT5B).
- Pubmed
- 25316809
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs