Annotation Detail
Information
- Associated Genes
- IL6
- Associated Variants
-
IL6 MUTATION
IL6 MUTATION - Associated Disease
- Macrophage Activation Syndrome
- Source Database
- DisGeNET
- Description
- While this therapy has caused toxicities, including cytokine release syndrome and macrophage activation syndrome, these conditions are reversible with IL-6 blockade using the monoclonal antibody tocilizumab.
- Pubmed
- 25455270
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs