Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA MUTATION
VEGFA MUTATION
Associated Disease
Colorectal cancer metastatic
Source Database
DisGeNET
Description
The VEGF- (bevacizumab) and EGFR- (cetuximab and panitumumab) targeting monoclonal antibodies have become integral components of the first-line treatment strategies for patients with metastatic colorectal cancer (mCRC).
Pubmed
25531050
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00868613990656971
Drugs