Annotation Detail
Information
- Associated Genes
- TYMS
- Associated Variants
-
TYMS MUTATION
TYMS MUTATION - Associated Disease
- Colorectal cancer metastatic
- Source Database
- DisGeNET
- Description
- The TYMS 2R/3G, 3C/3G or 3G/3G promoter variants were associated with worse PFS in the CRC (HR = 2.0, P < 0.01) and GEC group (HR = 5.4, P < 0.001) and worse OS in the GEC group (HR = 4.7, P < 0.001).
- Pubmed
- 25677447
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00352874433704394
Drugs