Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
SERPINE1 MUTATION
SERPINE1 MUTATION
Associated Disease
Acute coronary syndrome
Source Database
DisGeNET
Description
Healthy HDL inhibited thrombin-induced plasminogen activator inhibitor type 1 (PAI-1) expression, while HDL from ACS patients enhanced endothelial PAI-1 expression.
Pubmed
25056722
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00372424133900355
Drugs