Annotation Detail

Information
Associated Genes
ACE
Associated Variants
ACE MUTATION
ACE MUTATION
Associated Disease
essential hypertension
Source Database
DisGeNET
Description
The insertion/deletion (I/D) variant (rs4646994) of the angiotensin I-converting enzyme (ACE) gene is one of the most studied polymorphisms in relation to blood pressure and essential hypertension in humans.
Pubmed
21993364
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0332354605256359
Year of publication
2012
Drugs