Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
Associated Disease
Renal ischaemia
Source Database
DisGeNET
Description
Thus, an enhanced HMGB1-TLR4 pathway contributes to lung injury induced by bilateral nephrectomy and the other HMGB1-dependent pathway exists in pulmonary neutrophil infiltration caused by renal ischemia reperfusion.
Pubmed
24646859
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs