Annotation Detail

Information
Associated Genes
AGXT
Associated Variants
HNF1B c.544+1391T>C ( ENST00000613727.4, ENST00000621123.4, ENST00000614313.4, ENST00000617811.5 )
HNF1B c.345-1526G>A ( ENST00000617811.5, ENST00000614313.4, ENST00000621123.4, ENST00000613727.4 )
HIVEP3 c.-522+1405G>A, ENSG00000284895 c.68+1405G>A ( ENST00000372583.6, ENST00000643665.1, ENST00000372584.5, ENST00000646142.1 )
HNF1B c.544+1391T>C ( ENST00000613727.4, ENST00000614313.4, ENST00000617811.5, ENST00000621123.4 )
HNF1B c.345-1526G>A ( ENST00000613727.4, ENST00000614313.4, ENST00000617811.5, ENST00000621123.4 )
HIVEP3 c.-522+1405G>A, ENSG00000284895 c.68+1405G>A ( ENST00000372583.6, ENST00000372584.5, ENST00000643665.1, ENST00000646142.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
Besides, the haplotype-based analysis demonstrated that AGT in block rs752010-rs4430796-rs7501939 was associated with about 30% increase in T2D risk (OR 1.31, 95% CI 1.09-1.57, P = 0.01).
Pubmed
23300827
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Year of publication
2012
Drugs