Annotation Detail

Information
Associated Genes
CLOCK
Associated Variants
CLOCK MUTATION
CLOCK MUTATION
Associated Disease
Circadian Rhythm Disorders
Source Database
DisGeNET
Description
These findings suggest that in addition to structural abnormalities, lesion studies, and the large body of functional brain imaging studies reporting increased activation in the ACC of depressed patients who respond to a wide range of therapies, there may be a circadian dysregulation in clock gene expression in a subgroup of MDDs.
Pubmed
25349171
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs