Annotation Detail
Information
- Associated Genes
- CISH
- Associated Variants
-
MAPKAPK3 c.-436A>T
(
ENST00000446044.5 )
MAPKAPK3 c.-436A>T ( ENST00000446044.5 ) - Associated Disease
- malaria
- Source Database
- DisGeNET
- Description
- [When all five single-nucleotide polymorphisms (SNPs) (at positions -639, -292, -163, +1320, and +3415 all relative to CISH) within the CISH-associated locus were considered together in a multiple-SNP score, we found an association between CISH genetic variants and susceptibility to bacteremia, malaria, and tuberculosis (P=3.8x10(-11) for all comparisons), with -292 accounting for most of the association signal (P=4.58x10(-7)).]
- Pubmed
- 20484391
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.122367031978602
- Year of publication
- 2010
Drugs