Annotation Detail

Information
Associated Genes
CXCL8
Associated Variants
NC_000004.12:g.73740307A>T
NC_000004.12:g.73740307A>T
Associated Disease
tuberculosis
Source Database
DisGeNET
Description
A higher prevalence of purified protein derivative reactivity was associated with the TNF-α CCA/TCG haplotype (PR 1.298, 95%CI 1.059-1.589) and with the IL-10 AT/CC diplotype (PR 1.181, 95% CI 1.024-1.362), and the presence of the IL-8 rs4073 T allele was associated with protection against TB (PR 0.482, 95%CI 0.273-0.851).
Pubmed
25199010
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0105301511843394
Year of publication
2015
Drugs