Annotation Detail
Information
- Associated Genes
- TYMS
- Associated Variants
-
TYMS MUTATION
TYMS MUTATION - Associated Disease
- stomach carcinoma
- Source Database
- DisGeNET
- Description
- These polymorphisms have been related to the risk of suffering different cancers, for example leukemia, breast or gastric cancer, and response to different drugs, among which are methotrexate glutamates, stavudine, and specifically 5-fluorouracil (5-FU), as TYMS is its direct target.
- Pubmed
- 26166093
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0135720936040152
Drugs