Annotation Detail

Information
Associated Genes
CDH1
Associated Variants
CDH1 MUTATION
CDH1 MUTATION
Associated Disease
stomach carcinoma
Source Database
DisGeNET
Description
The risk of development of gastric cancer is high in families affected b-y these syndromes, but only hereditary diffuse gastric cancer is genetically explained (caused by germline alterations of CDH1, which encodes E-cadherin).
Pubmed
25638682
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0447879088932501
Drugs