Annotation Detail
Information
- Associated Genes
- VEGFA
- Associated Variants
-
CCL2 c.77-242_77-229delAGCTCCTCCTTCTC
(
ENST00000225831.4,
ENST00000580907.6 )
CCL2 c.77-242_77-229delAGCTCCTCCTTCTC ( ENST00000225831.4, ENST00000580907.6 )
rs833061
rs833061 - Associated Disease
- Diabetic Nephropathy
- Source Database
- DisGeNET
- Description
- Most of these eleven genetic variants were involved in GPCR signaling and receptor binding pathways whereas four were involved in chronic kidney failure. rs833061 [OR 2.08 (95% CI 1.63-2.66)] in the VEGFA gene and rs3917887 [OR 2.04 (95% CI 1.64-2.54)] in the CCL2 gene showed the most significant association with the risk of diabetic nephropathy.
- Pubmed
- 25280384
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.146584947723734
- Year of publication
- 2014
Drugs