Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
-
rs1919314
(
ENST00000417496.6,
ENST00000707077.1 )
rs10505477 ( ENST00000645438.1 )
rs1919314 ( ENST00000417496.6, ENST00000707077.1 )
rs10505477 ( ENST00000645438.1 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- No single nucleotide polymorphism (SNP) achieved a genome-wide significant P value; however, the most significantly associated SNPs were either previously associated with colorectal cancer in GWAS, such as rs10505477 in the gene POU5F1 [odds ratio (OR) = 0.87; 95% confidence interval (CI) 0.81-0.94; P = 4.4 × 10(-4)), or have been biologically linked to benign growths in other tissues, such as rs1919314 in the gene histone deacetylase 9 (OR = 1.32; 95% CI, 1.18-1.47; P = 1.1 × 10(-6)).
- Pubmed
- 23677573
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
- Year of publication
- 2013
Drugs