Annotation Detail

Information
Associated Genes
FCGR2B
Associated Variants
FCGR2B p.Ile232Thr (p.I232T) ( ENST00000236937.13, ENST00000367961.8, ENST00000358671.10 )
FCGR2B p.Ile232Thr (p.I232T) ( ENST00000236937.13, ENST00000358671.10, ENST00000367961.8 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
In humans, a SLE-associated polymorphism (rs1050501) results in a dysfunctional FcγRIIB(T232) receptor.
Pubmed
25475856
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.246507281952361
Year of publication
2015
Drugs