Annotation Detail

Information
Associated Genes
FCGR2B
Associated Variants
FCGR2B p.Ile232Thr (p.I232T) ( ENST00000236937.13, ENST00000367961.8, ENST00000358671.10 )
FCGR2B p.Ile232Thr (p.I232T) ( ENST00000236937.13, ENST00000358671.10, ENST00000367961.8 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
A single nucleotide polymorphism in human FcγRIIB (rs1050501) results in profound receptor dysfunction and is associated with systemic lupus erythematosus.
Pubmed
25022320
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.246507281952361
Year of publication
2014
Drugs