Annotation Detail

Information
Associated Genes
KIF1A
Associated Variants
KIF1A p.Thr99Met (p.T99M) ( ENST00000498729.9, ENST00000404283.9, ENST00000320389.12, ENST00000431776.7, ENST00000647572.2, ENST00000647731.1, ENST00000647885.1, ENST00000648047.2, ENST00000648129.1, ENST00000648364.1, ENST00000648680.1, ENST00000649096.1, ENST00000649306.1, ENST00000650053.1, ENST00000650130.1, ENST00000674907.2, ENST00000675126.2, ENST00000675940.2, ENST00000715177.1 )
KIF1A p.Thr99Met (p.T99M) ( ENST00000320389.12, ENST00000404283.9, ENST00000431776.7, ENST00000498729.9, ENST00000647572.2, ENST00000647731.1, ENST00000647885.1, ENST00000648047.2, ENST00000648129.1, ENST00000648364.1, ENST00000648680.1, ENST00000649096.1, ENST00000649306.1, ENST00000650053.1, ENST00000650130.1, ENST00000674907.2, ENST00000675126.2, ENST00000675940.2, ENST00000715177.1 )
Associated Disease
Muscle Spasticity
Source Database
DisGeNET
Description
A missense mutation in the KIF1A gene (p.Thr99Met) has been reported in a patient with intellectual disability (ID), axial hypotonia and peripheral spasticity.
Pubmed
25253658
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs