Muscle Spasticity
Information
- Disease name
- Muscle Spasticity
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06330311 | Active, not recruiting | N/A | Effectiveness of Whole-Body Vibration | March 29, 2024 | September 29, 2024 |
| NCT02418949 | Active, not recruiting | N/A | Altering Activation Patterns Post-stroke | November 2015 | December 2023 |
| NCT04907201 | Active, not recruiting | H-reflex in Spastic Lower Limb Cryoneurotomy | December 15, 2020 | November 2024 | |
| NCT04535479 | Active, not recruiting | N/A | Dry Needling for Spasticity in Stroke | September 8, 2020 | June 30, 2026 |
| NCT03521076 | Active, not recruiting | N/A | Randomized Controlled Trial of Virtual Reality | September 21, 2018 | December 2024 |
| NCT00210431 | Completed | Post Marketing Surveillance Study of Dysport | October 2004 | June 2006 | |
| NCT00216411 | Completed | Phase 4 | Effects on Quality of Life Following Dysport Treatment in Post-stroke Spasticity of the Arm | November 2004 | July 20, 2006 |
| NCT00223873 | Completed | N/A | The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury | November 2002 | July 2006 |
| NCT00234546 | Completed | Phase 4 | Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity | February 2003 | October 2007 |
| NCT00358293 | Completed | Phase 1/Phase 2 | Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity | December 2006 | February 2007 |
| NCT00535938 | Completed | MDs on Botox Utility (MOBILITY) | September 2007 | September 2013 | |
| NCT00549783 | Completed | Phase 4 | BOTOX® Economic Spasticity Trial (BEST) | October 2007 | July 2010 |
| NCT00557973 | Completed | Phase 2 | A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury | December 2007 | April 2009 |
| NCT00651690 | Completed | Phase 2 | Study of Responsiveness of Seven Functional Tasks in Patients With Poststroke Upper Limb Spasticity With Botulinum Toxin Type A Treatment | March 2004 | May 2005 |
| NCT00651729 | Completed | Phase 2 | Safety Study of Botulinum Toxin Type A for the Treatment of Focal Upper Limb Poststroke Spasticity | April 2003 | December 2004 |
| NCT01020500 | Completed | To Document the Effectiveness of BoNT-A Injection in Adult Subjects With Upper Limb Spasticity Following Stroke | January 2010 | May 2011 | |
| NCT01153022 | Completed | N/A | Effect of Joint Mobilization on Alpha Motoneuron Reflex Excitability | February 2008 | March 2009 |
| NCT01249417 | Completed | Phase 3 | Dysport® Pediatric Lower Limb Spasticity Study | July 2011 | June 2014 |
| NCT01251380 | Completed | Phase 3 | Dysport® Pediatric Lower Limb Spasticity Follow-on Study | October 2011 | January 2015 |
| NCT01256021 | Completed | Phase 4 | The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy | August 2010 | May 2011 |
| NCT01278576 | Completed | Phase 4 | Botulinum Toxin A Adult Gastrocnemius Muscle Study | January 2011 | May 2012 |
| NCT01383681 | Completed | Retrospective Study of Patients With Spasticity in the Spanish Population | February 2011 | October 2012 | |
| NCT01387074 | Completed | Observational Study of Botox® Treatment for Patients With Upper Limb Adult Spasticity | June 2011 | January 2013 | |
| NCT01412008 | Completed | N/A | Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle | March 2010 | June 2012 |
| NCT01509885 | Completed | Cyproheptadine and Chlorpromazine Effects on Spasticity | July 2010 | November 2012 | |
| NCT01575054 | Completed | Phase 3 | BOTOX® Treatment in Adult Patients With Post-Stroke Lower Limb Spasticity | May 2012 | July 2015 |
| NCT01587170 | Completed | Effects of Zolmitriptan on Sensory Transmission After Spinal Cord Injury | January 2012 | November 2012 | |
| NCT01603602 | Completed | Phase 3 | BOTOX® Treatment in Pediatric Upper Limb Spasticity | July 12, 2012 | July 6, 2017 |
| NCT01603615 | Completed | Phase 3 | BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity | October 30, 2012 | September 3, 2018 |
| NCT01603628 | Completed | Phase 3 | BOTOX® Treatment in Pediatric Lower Limb Spasticity | September 11, 2012 | June 28, 2017 |
| NCT01603641 | Completed | Phase 3 | BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity | November 5, 2012 | August 25, 2018 |
| NCT01683838 | Completed | Phase 3 | Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury | June 2002 | February 2004 |
| NCT01751373 | Completed | N/A | Assessment and Management of Post-Stroke Spasticity With Botulinum Toxin-A | May 2011 | November 2014 |
| NCT01803464 | Completed | N/A | Effect of Botox and Vibration on Bone in Children With Cerebral Palsy | March 2012 | February 2015 |
| NCT01882556 | Completed | Phase 2 | Early Use of Botulinum Toxin in Spasticity Post Stroke. | January 2012 | May 2014 |
| NCT01915342 | Completed | N/A | Developing Optimal Focal Muscle Vibration for Improving Spasticity | August 2013 | September 2014 |
| NCT01930786 | Completed | An Adult Spasticity Registry of OnabotulinumtoxinA Treatment | October 16, 2013 | October 9, 2017 | |
| NCT01968902 | Completed | Phase 4 | Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients | November 2013 | December 31, 2016 |
| NCT02043145 | Completed | Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea | July 2008 | April 2012 | |
| NCT02934646 | Completed | Phase 2 | Powered Exoskeleton for the Treatment of Elbow Spasticity | July 2014 | July 2016 |
| NCT00041717 | Completed | Phase 3 | Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury | July 2002 | May 2004 |
| NCT00047580 | Completed | Phase 3 | Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity. | June 2002 | September 2002 |
| NCT00060957 | Completed | Phase 2 | Botulinum Toxin (BOTOX) for Cerebral Palsy | July 1997 | |
| NCT00076687 | Completed | Phase 2 | Safety Study of Botulinum Toxin Type A in Post-Upper Limb Stroke Patients With Reduced Lung Function | October 2003 | August 2009 |
| NCT02408900 | Completed | Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function | March 25, 2015 | August 3, 2015 | |
| NCT02462317 | Completed | Phase 4 | Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment | April 2015 | December 9, 2020 |
| NCT02546999 | Completed | Phase 4 | Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy? | September 2015 | October 15, 2021 |
| NCT02719483 | Completed | N/A | Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy | April 2014 | March 2016 |
| NCT02757404 | Completed | Phase 4 | Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity | May 30, 2016 | August 16, 2016 |
| NCT02903823 | Completed | Phase 4 | Intrathecal (IT) Baclofen Drug Distribution | April 22, 2016 | February 1, 2019 |
| NCT02907775 | Completed | N/A | Multi-channel Stimulation for Post Stroke Spasticity (MUSTS) | September 30, 2016 | September 30, 2018 |
| NCT00014976 | Completed | Physiologic Studies of Spasticity | April 13, 2001 | November 1, 2010 | |
| NCT03080454 | Completed | Phase 1/Phase 2 | The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke | September 2016 | March 2018 |
| NCT03209960 | Completed | Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity | January 30, 2018 | August 1, 2018 | |
| NCT03211390 | Completed | Using Telemedicine to Improve Spasticity Diagnosis Rates | January 30, 2018 | August 1, 2018 | |
| NCT03250988 | Completed | Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility | January 30, 2018 | August 1, 2018 | |
| NCT03289702 | Completed | Phase 3 | CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3) | November 13, 2017 | November 9, 2018 |
| NCT03814460 | Completed | Stroke and Assessment of Muscle Tone | February 2, 2019 | August 25, 2019 | |
| NCT03916770 | Completed | N/A | The Effect of Whole Body Vibration (WBV) on Spasticity in Poststroke Hemiplegia | August 1, 2019 | August 1, 2020 |
| NCT04036981 | Completed | Muscle Selection for Botulinum Toxin A Injection in Poststroke Elbow Flexor Spasticity | May 10, 2019 | June 1, 2021 | |
| NCT04090892 | Completed | Effects of Soft Tissue Lengthening on Gait in Children With Spasticity | May 10, 2016 | January 31, 2017 | |
| NCT04543448 | Completed | N/A | Effect of Cervical Mobilization on Balance and Plantar Pressure Distribution in Multiple Sclerosis | October 2, 2019 | August 20, 2020 |
| NCT04780191 | Completed | N/A | Investigation of Treatment Using the MyoRegulator® Device in Patients With Spasticity in the Lower Limb Due to Stroke | July 19, 2018 | January 19, 2021 |
| NCT05164003 | Completed | Phase 1 | CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1) | July 17, 2017 | September 29, 2017 |
| NCT05295563 | Completed | Effects of Repeated Botulinum Toxin Injections in Children With Cerebral Palsy | May 1, 2021 | May 31, 2022 | |
| NCT05510726 | Completed | Quantitative Evaluation of Muscle Stiffness in Neurological Patients With Muscle Overactivity | September 1, 2022 | May 30, 2023 | |
| NCT05546190 | Completed | A Study to Collect Participants Experience of Living With Adult Upper Limb (AUL) Spasticity and to Assess the Arm Activity Measure (ArmA) | September 20, 2022 | March 23, 2023 | |
| NCT05889026 | Completed | N/A | The Effect of Extracorporeal Shock Wave Therapy After Botulinum Toxin Type A Injection for Post-stroke Spasticity | August 6, 2020 | September 8, 2021 |
| NCT06048432 | Completed | N/A | Tele-physiotherapy on Post-stroke Hemiplegia Patients | January 1, 2020 | January 31, 2022 |
| NCT03660969 | Recruiting | Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease | January 1, 2018 | January 1, 2027 | |
| NCT03783572 | Recruiting | N/A | Upper-limb Active Function and Botulinum Toxin A | December 8, 2020 | December 30, 2027 |
| NCT06117020 | Recruiting | Phase 1 | Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals | September 11, 2023 | May 2024 |
| NCT06163950 | Recruiting | N/A | The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability | May 2, 2023 | October 31, 2024 |
| NCT05497609 | Recruiting | The Muscle in Children With Cerebral Palsy - Longitudinal Exploration of Microscopic Muscle Structure. | January 15, 2006 | December 15, 2027 | |
| NCT03096197 | Recruiting | N/A | Exoskeleton and Spinal Cord Stimulation for SCI | March 30, 2017 | September 2025 |
| NCT05506228 | Recruiting | How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery. | January 15, 2002 | December 15, 2033 | |
| NCT04742257 | Recruiting | N/A | Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity | March 4, 2022 | December 31, 2025 |
| NCT03306615 | Recruiting | Phase 2 | Peripheral Modulation of Muscle Stiffness and Spasticity | October 11, 2021 | November 16, 2024 |
| NCT03367429 | Terminated | Phase 4 | The Movement of Botulinum Toxin Through the Lateral Gastrocnemius Muscle in Humans: An Expanded Examination | June 15, 2018 | September 18, 2019 |
| NCT00893776 | Terminated | N/A | Bilateral Versus Unilateral Task Retraining Using the SaeboFlex Orthosis | June 2009 | December 2014 |
| NCT00531466 | Terminated | Phase 2 | Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury | September 2007 | November 2008 |
| NCT04502927 | Terminated | N/A | Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients | March 10, 2020 | March 18, 2020 |
| NCT02145676 | Terminated | Phase 3 | OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity | May 2014 | December 2015 |
| NCT00552604 | Terminated | Phase 3 | MUltiple Sclerosis and Extract of Cannabis (MUSEC) Study | June 2006 | November 2008 |
| NCT00532532 | Terminated | Phase 2 | Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis | September 2007 | November 2008 |
| NCT04530955 | Unknown status | N/A | Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS) | September 24, 2020 | June 2023 |
| NCT03816787 | Unknown status | N/A | Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain | December 1, 2019 | May 29, 2021 |
| NCT04378946 | Unknown status | N/A | Error Augmentation Motor Learning Training Approach in Stroke Patients | September 1, 2020 | August 31, 2023 |
| NCT02462018 | Unknown status | Phase 4 | Effects of Functional Electrical Stimulation on Gait in Children With Cerebral Palsy | May 2015 | July 2017 |
| NCT02736747 | Unknown status | N/A | Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects | April 2016 | March 2018 |
| NCT02505802 | Unknown status | Phase 4 | The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults | January 2014 | January 2017 |
| NCT01041157 | Unknown status | Phase 1 | Botulinum Toxin Injection Efficiency | September 2008 | December 2011 |
| NCT02145689 | Withdrawn | Phase 3 | Long-Term Study of OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity | August 2014 | May 2017 |
| NCT02145650 | Withdrawn | Spasticity Registry Evaluating Epidemiology, Treatment Patterns and Clinical Needs | May 2014 | August 2015 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D009128