Annotation Detail

Information
Associated Genes
TLR1
Associated Variants
TLR1 MUTATION
TLR1 MUTATION
Associated Disease
Carcinoma of lung
Source Database
DisGeNET
Description
We mainly elucidate that miRNA-15a/16 can enhance radiation sensitivity by regulating the TLR1/NF-κB signaling pathway and act as a potential therapeutic approach to overcome radioresistance for lung cancer treatment.
Pubmed
25442346
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs