Annotation Detail

Information
Associated Genes
CDKN2A
Associated Variants
CDKN2A MUTATION
CDKN2A MUTATION
Associated Disease
Carcinoma of lung
Source Database
DisGeNET
Description
Furthermore, comparative analysis of mutant Kras;Cdkn2a null with Kras;Cdkn2ab null mice and experiments with mutant KRAS;CDKN2AB-deficient human lung cancer cells indicated that p15INK4B is a critical tumor suppressor.
Pubmed
24618618
Section of the abstract supporting the evidence
UNLABELLED
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0297826610587127
Drugs