Annotation Detail

Information
Associated Genes
STAT3
Associated Variants
STAT3 MUTATION
STAT3 MUTATION
Associated Disease
breast carcinoma
Source Database
DisGeNET
Description
The efficiency of PEI/STAT3-siRNA polyplexes in the induction of STAT3 associated cell death in wild type and drug-resistant MDA-MB-435 breast cancer cells as monotherapy and upon combination with chemotherapeutic agents, doxorubicin and paclitaxel, was also investigated.
Pubmed
24167124
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0266013034638697
Drugs