Annotation Detail

Information
Associated Genes
MAPK1
Associated Variants
MAPK1 MUTATION
MAPK1 MUTATION
Associated Disease
Epithelial ovarian cancer
Source Database
DisGeNET
Description
In conclusion, CrkL protein is required for TGF-β signal pathways through AKT and ERK pathway, which can mediate the development of epithelial ovarian carcinomas.
Pubmed
25307974
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs