Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
Hashimoto Disease
Source Database
DisGeNET
Description
A significant association was found between the allele A in TNFA-308 G/A and Hashimoto's thyroiditis, both in the dominant (OR = 1.82, CI = 1.37-2.43, p-value = 4.4×10(-5)) and log-additive (OR = 1.64, CI = 1.28-2.10, p-value = 8.2×10(-5)) models.
Pubmed
25127106
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00554838957344497
Drugs