Annotation Detail

Information
Associated Genes
MAPK1
Associated Variants
MAPK1 MUTATION
MAPK1 MUTATION
Associated Disease
Hashimoto Disease
Source Database
DisGeNET
Description
Furthermore, BAG3 knockdown increased the HT-induced phosphorylation of ERK after HT treatment, and the ERK inhibitor U0126 significantly improved the viability of the cells treated with a combination of BAG3 knockdown and HT.
Pubmed
25471019
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs