Annotation Detail
Information
- Associated Genes
- ALOX5
- Associated Variants
-
ALOX5 MUTATION
ALOX5 MUTATION - Associated Disease
- prostate carcinoma
- Source Database
- DisGeNET
- Description
- Wedelolactone, a plant coumestan, was shown to act as anti-cancer agent for breast and prostate carcinomas in vitro and in vivo targeting multiple cellular proteins including androgen receptors, 5-lipoxygenase and topoisomerase IIα.
- Pubmed
- 25934092
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs