Annotation Detail

Information
Associated Genes
PIK3CA
Associated Variants
PIK3CA MUTATION
PIK3CA MUTATION
Associated Disease
prostate carcinoma
Source Database
DisGeNET
Description
Among the cancer networks and STNs we considered, it is found that there is a substantial amount of crosstalking through motif interconnections, in particular, the crosstalk between prostate cancer network and PI3K-Akt STN.To validate the role of network motifs in cancer formation, several examples are presented which demonstrated the effectiveness of the present approach.
Pubmed
25707690
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0171008379410591
Drugs